Temple Mount, the 35-acre (14 ha) compound which is one of the world's most holy sites, is revered by Christian, Muslims and Jews. Jews believe that God used dust from the hill to created Adam and Eve. Muslims believe Muhammad ascended to heaven from here. The site of the Temple of Solomon and later Herod's Temple, it was controlled by the Knights Templar during the Crusades. The Dome of the Rock, which has generally been off limits to non-Muslims, and Al Aqsa Mosque are also on Temple Mount and part of a UNESCO World Heritage Site. Visiting is well worth the lines (get there early) and the uncertainty of opening hours. In any case, dress modestly and do not arrive with prayer books. Check locally for accessibility before you queue and expect tight security.
Added 3 years ago
You can only visit Saturday-Thursday from 7:30-10:30 in the morning but it is well worth the time. They discourage outward signs of religious imagery and or bringing bibles. Dome of the Rock is the oldest mostly intact Islamic shrine in the world and the marbles and mosaics which decorate its walls are incredible close up. Non-Muslims are not allowed inside the shrine.