Take the walk-up private car service from the airport - which includes limousines, SUVs, and town cars - to the Encore Wynn Las Vegas, where there's a Pride concierge to help you plan your Vegas itinerary. If you'd rather be close to the museums and art galleries of Downtown, stay at Main Street Station Hotel. This is one of the best bargains in the city, and just two short blocks from several sites of interest.
The second stop is Jazz Brunch at The Country Club, a four-star restaurant on the grounds of sister hotel the Wynn, where Chef Carlos Guia serves high-end Cajun-Creole dishes while a live band plays jazz favorites. Those who want waterfall views should sit outside on the terrace.
Spend some time at the spas Las Vegas is known for. Try the indulgent full-body botanic scrub at Canyon Ranch spa, or check out Saffron Day Spa, a more budget-friendly option with loyal customers.
For a little Las Vegas history, head north to the Mob Museum and the Neon Graveyard - especially interesting for architecture buffs, with behind-the-scenes information about the birth and growth of the glitter that defines Las Vegas.
By now you'll be hungry enough for dinner at Lotus of Siam, a northern Thai restaurant hidden in a strip mall on the East side that's achieved cult status with local foodies. The prices are dirt cheap and the portions generous, but their wine list has a number of good bottles on hand to match the spice of the meal.
After dinner head back to your hotel for a night cap at XS, one of the Encore's on-site nightclubs. The vibe here is upscale and trendy, and the open-air dance floor and pool-side cabanas are the perfect place to relax after a full day.