Grab a cab from the airport to Mandalay Bay - named by Out Traveler as the best hotel in Las Vegas, its proven so popular with LGBT tourists it's often called the Mandalay Gay. The high-energy pool area and Cirque du Soleil attractions make it the perfect home base for a party animal.
Set your sights to brunch at Mon Ami Gabi, a French bistro with fantastic views of the Bellagio fountains. The outdoor patio scene is young, lively, and ideal for people-watching.
Next, head to the Luxor for an afternoon by the pool at Temptation, a 21-and-over open-air gay entertainment venue with international DJs and bottle-service. Host J.Son emcees a number of fun activities like hot body contests, fashion shows, and volleyball games, and the party ends around sunset so there's time to rest up before heading out for the evening.
Start the night with dinner at Sage, chef Shawn McClain's opulent new seafood restaurant. The bartenders here really know what they're doing, so be sure to try one of their cocktails made with fresh fruit purees and hand-muddled spirits.
For an after-hours experience, stop in at Share nightclub west of the Strip, where the action gets a little hotter with private rooms, a garden area for cruising, and several separate dance floors. It's the perfect place to wind down the night and catch an impromptu drag show.