Bristol

Bella Vista

A regular on best-hotel lists, The Bristol in the financial district has the aura of a historic private mansion with a rich colonial past. The 125 rooms are...

  • LGBTQ-friendly
  • Luxury Hotel

Hotel Riu Plaza Panama

Calle 50

Its 23 conference rooms and financial district location make Hotel Riu Plaza a natural for international business types. The hotel offers three restaurants,...

  • LGBTQ-friendly
  • International brand

Luna's Castle

Casco Viejo

Located at the entrance to the historic district of Casco Viejo with views to the Bay of Panama, Luna's Castle is a laid-back backpacker hostel housed in a former...

  • LGBTQ-friendly
  • Hostel

Las Clementinas

Casco Viejo

Built in the 1930s as an apartment building, Las Clementinas in Casco Viejo has been converted into spacious suites with fully equipped kitchens.  Both locals...

  • LGBTQ-friendly
  • Boutique hotel

Gamboa Rainforest Resort

Gamboa

On the edge of the jungle near the Panama Canal, the Gamboa Rainforest Hotel is a destination in itself but also a good launching site for excursions to the...

  • LGBTQ-friendly
  • Resort

Intercontinental Miramar

Avenida Balboa

The first skyscraper on Panama's dramatic skyline, the 56-floor Intercontinental Miramar remains the grande dame of the city's hotel scene as it surveys Panama Bay...

  • LGBTQ-friendly
  • International brand

Le Meridien

Avenida Balboa, Bella Vista

At the corner of Calle Uruguay and Avenida Balboa, the 111-room Le Meridien is ideally located for anyone who wants to savor Panamanian nightlife but also jog, bike...

  • LGBTQ-friendly
  • International brand

Sheraton Panama Hotel & Convention Center

San Francisco

Directly across the street from the Atlapa Convention Center, the sleek Sheraton Panama Hotel is in the upscale San Francisco neighborhood just off the toll road to...

  • LGBTQ-friendly
  • Business & Convention

Aloft Panama

San Francisco

A limited-service hotel with no bellboys, concierge or room service, Aloft Panama still manages to generate a glitzy vibe in a bar with signature drinks and a lounge...

  • LGBTQ-friendly
  • International brand

American Trade Hotel

Casco Viejo

The glitzy 50-room American Trade Hotel, which opened in 2013, overlooks Plaza Herrera in Casco Viejo. Hard to believe surveying the skyline today, but the restored...

  • LGBTQ-friendly
  • Boutique hotel

Balboa Inn

Ancon

LGBT-friendly, the nine-room Balboa Inn in the former Canal Zone is run by Dutch/British ex-pats. All rooms have European mattresses and both A/C and ceiling fans....

  • LGBTQ-friendly
  • Bed & Breakfast

Canal Inn

Ancon

LGBT-friendly, the 15-room Canal Inn is under the Bridge of the Americas in a quiet residential neighborhood close to Amador Causeway, Ancón Hill, Albrook Mall, the...

  • LGBTQ-friendly
  • Bed & Breakfast

Canopy Tower

Ancon

At the Canopy Tower, the eco-lodge housed in a former US radar station on Semaphore Hill in the Soberania National Forest, rooms are identified not by floor but by...

  • LGBTQ-friendly
  • Eco Hotel

Casa Sucre

Casco Viejo

LGBT-friendly, Casa Sucre is a five-bedroom, three-apartment guesthouse in a restored 19th century home in Casco Viejo.  It recently added a coffee house...

  • LGBTQ-friendly
  • Bed & Breakfast

Country Inn & Suites Panama Canal

Amador

Country Inn & Suites Panama at the entrance to the Amador Causeway in Balboa offers up-close-and-personal views of Panama Canal traffic. The 83 guest rooms have...

  • LGBTQ-friendly
  • International brand

Grace Panama

Obarrio

Occupying the ground floor plus six upper floors of the avant-garde Twist Tower near Panama's financial district, the 60-room Grace Panama is already a Panama...

  • LGBTQ-friendly
  • Boutique hotel

Hard Rock Hotel Panama Megapolis

Bella Vista

Near Avenida Balboa and the bay, the 1,463-room, 66-floor Hard Rock Hotel Panama Megapolis is entertainment central with eight bars and lounges, four restaurants, a...

  • LGBTQ-friendly
  • International brand

Hilton Garden Inn

El Cangrejo

Close to the financial district and two blocks Via Espana shops, the Hilton Garden Inn is a five-minute walk from the Panama Metro Station. Its 14 floors have 170...

  • LGBTQ-friendly
  • International brand

Hilton Panama

Avenida Balboa

The 70-story Hilton Panama on Avenida Balboa offers stunning vistas of the city, Panama Bay and the Pacific Ocean. Its 347 rooms are designed for comfort with...

  • LGBTQ-friendly
  • International brand

Holiday Inn Panama Canal

City of Knowledge

This Holiday Inn, just across the road from the Miraflores Locks, offers views of the Panama Canal and suburban tranquility. Located in the City of Knowledge in...

  • LGBTQ-friendly
  • International brand

Hotel Deville

Marbella

With its red awning and mansard roof, the four-story Hotel Deville brings Old World charm in the heart of the financial district. The hotel has 33 individually...

  • LGBTQ-friendly
  • Bed & Breakfast

Las Vegas Suites Hotel

El Cangrejo

Located in the jumping El Cangrejo neighborhood, Las Vegas Suites Hotels is close by the Veneto and Fiesta Casinos, discos, restaurants, shopping and Via Espana, one...

  • LGBTQ-friendly
  • Suite Hotel

Los Cuatro Tulipanes

Casco Viejo

Los Cuatro Tulipanes, a multi-property guesthouse run by knowledgeable ex-pats, arranges rentals of luxury apartments in beautifully restored colonial buildings in...

  • LGBTQ-friendly
  • Apartments - Aparthotel

Magnolia Inn

Casco Viejo

American ex-pats run this hostel/hotel combo in a restored colonial mansion just off Cathedral Square in Casco Viejo. Accommodations are include luxury hostel rooms,...

  • LGBTQ-friendly
  • Inn

Manrey Boutique Hotel

Calle Uruguay, Bella Vista

Two blocks from Avenida Balboa and convenient to restaurant and nightlife, the 35-room Manrey has a sleek black façade and striking interiors that come with high-end...

  • LGBTQ-friendly
  • Boutique hotel

Marriott Panama

Marbella

The 20-story Panama Marriott Hotel is centrally located in the financial district.  Décor in the 287 guest rooms is traditional but with special touches like...

  • LGBTQ-friendly
  • International brand

Radisson Decapolis

Avenida Balboa

Near Avenida Balboa and the bay, the 29-floor Radisson Decapolis has 240 smoke-free rooms with chic, modern design and city and sea views. An air-conditioned...

  • LGBTQ-friendly
  • International brand

Riande Aeropuerto

Tocumen Airport

Three minutes from the international airport, the 178-room Riande Aeropeuerto provides the basics in comfortable rooms offering courtyard, pool or mountain views and...

  • LGBTQ-friendly
  • International brand

Sortis Hotel, Spa & Casino

Obarrio

Known for its brunches and huge poker room, the glitzy Sortis opened in 2014 in the heart of the banking district. It offers 391 rooms, suites and apartments on 22...

  • LGBTQ-friendly
  • Business & Convention

Tantalo Hotel / Kitchen / Rooftop Bar

Casco Viejo

LGBT-friendly, the boho-chic Tantalo Hotel in Casco Viejo has 12 rooms, each designed by a different artist and the old quarter's only rooftop bar where it's always...

  • LGBTQ-friendly
  • Boutique hotel